Structure of PDB 3rzl Chain A Binding Site BS02

Receptor Information
>3rzl Chain A (length=194) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SHSWRHIRAEGLDSSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFG
KWHSVPRKQATYGDAGLTYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTF
NFVLINRYKDGSDHICEHRDDERELAPGSPIASVSFGASRDFVFRHKAVV
RLPLAHGSLLMMNHPTNTHWYHSLPVRKKVLAPRVNLTFRKILL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3rzl Duplex interrogation by a direct DNA repair protein in search of base damage
Resolution2.6 Å
Binding residue
(original residue number in PDB)		Q100 F102 G103 R176 R241 K243
Binding residue
(residue number reindexed from 1)		Q47 F49 G50 R123 R177 K179
Enzymatic activity
Enzyme Commision number 1.14.11.33: DNA oxidative demethylase.
Gene Ontology

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Biological Process
External links
PDB RCSB:3rzl, PDBe:3rzl, PDBj:3rzl
PDBsum3rzl
PubMed22659876
UniProtQ6NS38|ALKB2_HUMAN DNA oxidative demethylase ALKBH2 (Gene Name=ALKBH2)

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