Structure of PDB 3rf3 Chain A Binding Site BS02

Receptor Information
>3rf3 Chain A (length=257) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAV
SNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYS
VPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVV
ETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKEL
LPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLT
SWDEDAW
Ligand information
>3rf3 Chain D (length=24) Species: 623 (Shigella flexneri) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
TRETIFEASKKVTNSLSNLISLIG
Receptor-Ligand Complex Structure
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PDB3rf3 Novel vinculin binding site of the IpaA invasin of Shigella.
Resolution1.61 Å
Binding residue
(original residue number in PDB)		R7 Q180 Q185 R188
Binding residue
(residue number reindexed from 1)		R6 Q179 Q184 R187
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003779 actin binding
GO:0005198 structural molecule activity
GO:0051015 actin filament binding
Biological Process
GO:0007155 cell adhesion
Cellular Component
GO:0015629 actin cytoskeleton

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3rf3, PDBe:3rf3, PDBj:3rf3
PDBsum3rf3
PubMed21525010
UniProtP18206|VINC_HUMAN Vinculin (Gene Name=VCL)

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