Structure of PDB 3r9x Chain A Binding Site BS02

Receptor Information

>3r9x Chain A (length=302) Species: 63363 (Aquifex aeolicus)

HMKVGYVAIVGKPNVGKSTLLNNLLGTKVSIISPKAGTTRMRVLGVKNIP
NEAQIIFLDTPGIYEPKKSDVLGHSMVEIAKQSLEEADVILFMIDATEGW
RPRDEEIYQNFIKPLNKPVIVVINKIDKIGPAKNVLPLIDEIHKKHPELT
EIVPISALKGANLDELVKTILKYLPEGEPLFPEDMITDLPLRLLAAEIVR
EKAMMLTREEVPTSIAVKINEIKPGDANPNMLVIKGEIIVDRENLKPIII
GKKGQRLKEIGKRARQELELILGRPVYLELWVKVVPDWRRRPEYVRLFGY
AL

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 3r9x Chain A Residue 401

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3r9x The Era GTPase recognizes the GAUCACCUCC sequence and binds helix 45 near the 3' end of 16S rRNA.
• Resolution: 2.8 Å
• Binding residue (original residue number in PDB): S17 T38
• Binding residue (residue number reindexed from 1): S18 T39
• Annotation score: 1

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003924 GTPase activity
• GO:0005525 GTP binding
• GO:0019843 rRNA binding
• GO:0043024 ribosomal small subunit binding
• GO:0070181 small ribosomal subunit rRNA binding

Biological Process

• GO:0000028 ribosomal small subunit assembly
• GO:0042254 ribosome biogenesis
• GO:0042274 ribosomal small subunit biogenesis

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005886 plasma membrane

External links

• PDB: RCSB:3r9x, PDBe:3r9x, PDBj:3r9x
• PDBsum: 3r9x
• PubMed: 21646538
• UniProt: O67800|ERA_AQUAE GTPase Era (Gene Name=era)