Structure of PDB 3qz7 Chain A Binding Site BS02
Receptor Information
>3qz7 Chain A (length=341) Species:
2287
(Saccharolobus solfataricus) [
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MIVLFVDFDYFYAQVEEVLNPSLKGKPVVVCVFSGRFEDSGAVATANYEA
RKFGVKAGIPIVEAKKILPNAVYLPMRKEVYQQVSSRIMNLLREYSEKIE
IASIDEAYLDISDKVRDYREAYNLGLEIKNKILEKEKITVTVGISKNKVF
AKIAADMAKPNGIKVIDDEEVKRLIRELDIADVPGIGNITAEKLKKLGIN
KLVDTLSIEFDKLKGMIGEAKAKYLISLARDEYNEPIRTRVRKSIGRIVT
MKRNSRNLEEIKPYLFRAIEESYYKLDKRIPKAIHVVAVTEDLDIVSRGR
TFPHGISKETAYSESVKLLQKILEEDERKIRRIGVRFSKFI
Ligand information
>3qz7 Chain T (length=15) [
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gcctcgatcagtgcc
Receptor-Ligand Complex Structure
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PDB
3qz7
The y-family DNA polymerase dpo4 uses a template slippage mechanism to create single-base deletions.
Resolution
1.998 Å
Binding residue
(original residue number in PDB)
V32 Q82 E219 A220 R242 K243 S244 R247 T250 K275 R332
Binding residue
(residue number reindexed from 1)
V32 Q82 E219 A220 R242 K243 S244 R247 T250 K275 R332
Enzymatic activity
Enzyme Commision number
2.7.7.7
: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0000287
magnesium ion binding
GO:0003677
DNA binding
GO:0003684
damaged DNA binding
GO:0003887
DNA-directed DNA polymerase activity
GO:0046872
metal ion binding
Biological Process
GO:0006260
DNA replication
GO:0006261
DNA-templated DNA replication
GO:0006281
DNA repair
GO:0006974
DNA damage response
GO:0042276
error-prone translesion synthesis
Cellular Component
GO:0005737
cytoplasm
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:3qz7
,
PDBe:3qz7
,
PDBj:3qz7
PDBsum
3qz7
PubMed
21421759
UniProt
Q97W02
|DPO4_SACS2 DNA polymerase IV (Gene Name=dbh)
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