Structure of PDB 3qln Chain A Binding Site BS02

Receptor Information
>3qln Chain A (length=123) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GIVSCTACGQQVNHFQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGM
DEQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRRELSTIMDENNQWYCY
ICHPEPLLDLVTACNSVYENLEQ
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3qln Chain A Residue 2 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3qln ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome
Resolution1.901 Å
Binding residue
(original residue number in PDB)		C220 C223 C243
Binding residue
(residue number reindexed from 1)		C54 C57 C77
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
External links
PDB RCSB:3qln, PDBe:3qln, PDBj:3qln
PDBsum3qln
PubMed21666679
UniProtP46100|ATRX_HUMAN Transcriptional regulator ATRX (Gene Name=ATRX)

[Back to BioLiP]