Structure of PDB 3q7c Chain A Binding Site BS02

Receptor Information
>3q7c Chain A (length=209) Species: 11622 (Lassa virus Josiah) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GFTAGLTYSQLMTLKDAMLQLDPNAKTWMDIEGRPEDPVEIALYQPSSGC
YIHFFREPTDLKQFKQDAKYSHGIDVTDLFATQPGLTSAVIDALPRNMVI
TCQGSDDIRKLLESQGRKDIKLIDIALSKTDSRKYENAVWDQYKDLCHMH
TGVVVEKKKRGGKEEITPHCALMDCIMFDAAVSGGLNTVLRAVLPRDMVF
RTSTPRVVL
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain3q7c Chain A Residue 2 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3q7c Structure of the Lassa virus nucleoprotein reveals a dsRNA-specific 3' to 5' exonuclease activity essential for immune suppression.
Resolution1.5 Å
Binding residue
(original residue number in PDB)		D389 E391 D533
Binding residue
(residue number reindexed from 1)		D30 E32 D174
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.13.-
External links
PDB RCSB:3q7c, PDBe:3q7c, PDBj:3q7c
PDBsum3q7c
PubMed21262835
UniProtP13699|NCAP_LASSJ Nucleoprotein (Gene Name=N)

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