Structure of PDB 3pvp Chain A Binding Site BS02

Receptor Information
>3pvp Chain A (length=96) Species: 419947 (Mycobacterium tuberculosis H37Ra) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ISAATIMAATAEYFDTTVEELRGPGKTRALAQSRQIAMYLCRELTDLSLP
KIGQAFGRDHTTVMYAQRKILSEMAERREVFDHVKELTTRIRQRSK
Ligand information
Receptor-Ligand Complex Structure
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PDB3pvp Structural and Thermodynamic Signatures of DNA Recognition by Mycobacterium tuberculosis DnaA.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		K436 R438 R452 S458 L459 P460 H470 M474
Binding residue
(residue number reindexed from 1)		K26 R28 R42 S48 L49 P50 H60 M64
Binding affinityPDBbind-CN: Kd=60nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003688 DNA replication origin binding
GO:0005524 ATP binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006270 DNA replication initiation
GO:0006275 regulation of DNA replication

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Molecular Function
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Biological Process
External links
PDB RCSB:3pvp, PDBe:3pvp, PDBj:3pvp
PDBsum3pvp
PubMed21620858
UniProtA5TY69|DNAA_MYCTA Chromosomal replication initiator protein DnaA (Gene Name=dnaA)

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