Structure of PDB 3pit Chain A Binding Site BS02

Receptor Information
>3pit Chain A (length=168) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LPTYKLVVVGDGGVGKSALTIQFFQKIFVPEYDPTIEDSYLKHTEIDNQW
AILDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLI
LRVKDRESFPMILVANKVDLMHLRKVTRDQGKEMATKYNIPYIETSAKDP
PLNVDKTFHDLVRVIRQQ
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain3pit Chain A Residue 180 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3pit Crystal structure of M-RasD41E in complex with GppNHp (type 2)
Resolution1.55 Å
Binding residue
(original residue number in PDB)		S27 T45
Binding residue
(residue number reindexed from 1)		S17 T35
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3pit, PDBe:3pit, PDBj:3pit
PDBsum3pit
PubMed
UniProtO08989|RASM_MOUSE Ras-related protein M-Ras (Gene Name=Mras)

[Back to BioLiP]