Structure of PDB 3pih Chain A Binding Site BS02

Receptor Information
>3pih Chain A (length=836) Species: 2336 (Thermotoga maritima) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NEIVVKGARVHNLKNITVRIPKNRLVVITGVSGSGKSSLAMDTIYAEGQR
RYLESLSTYKKPDVDEIEGLSPAIAIDQKTSHNPRSTVGTVTEIYDYLRV
LYARIGKAHCPECGRPLEKKSIDEILQDLFNSFKEGSRIYILAPLVVDRL
ILETRNEHRILDSLELAMREGKGFVEIRNVDTGESKIFSENLMCPVCGIG
FPEITPKLFSFNSPYGACPNCHGLGFTFEVDPSLVAIIPYRWDRRLSRWV
AREIEKRGVSPPEDVKEFILYGDFEGVVPKVQRWHRETEMKEWLEKNFIV
QRTCSVCGGRRLNREALSVKINGLNIHEFTELSISEELEFLKNLNLTERE
REIVGELLKEIEKRLEFLVDVGLEYLTLSRSATTLSGGESQRIRLATQIG
SGLTGVIYVLDEPTIGLHPRDTERLIKTLKKLRDLGNTVIVVEHDEEVIR
NADHIIDIGPGGGTNGGRVVFQGTVDELLKNPDSSLTGEYLSGKRKITVN
KTRRLPYASLKIKGVRHNNLKNIDVEIPLGVFVCVTGVSGSGKSSLVMET
LYPALMNLLHKTKLPAGEFDSIEGHENIDKMIAIDQSPIGRTPRSNPATY
TKVFDEIRSLFAMTPAAKARGYNKSRFSFNLKGGRCEACQGQGYVKIEML
FLPDVYVECDVCKGKRYNRETLEITYKGKNISDILDMTVDEALEFFKNIP
SIKRTLQVLHDVGLGYVKLGQPATTLSGGEAQRIKLASELRKRDTGRTLY
ILDEPTVGLHFEDVRKLVEVLHRLVDRGNTVIVIEHNLDVIKNADHIIDL
GPEGGKEGGYIVATGTPEEIAKNPHSYTGRFLKNVL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3pih Chain A Residue 917 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3pih Structure of UvrA nucleotide excision repair protein in complex with modified DNA.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		C716 C719 C739 C742
Binding residue
(residue number reindexed from 1)		C636 C639 C659 C662
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003824 catalytic activity
GO:0004518 nuclease activity
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0009381 excinuclease ABC activity
GO:0016887 ATP hydrolysis activity
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair
GO:0006289 nucleotide-excision repair
GO:0009432 SOS response
Cellular Component
GO:0005737 cytoplasm
GO:0009380 excinuclease repair complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3pih, PDBe:3pih, PDBj:3pih
PDBsum3pih
PubMed21240268
UniProtQ9WYV0|UVRA_THEMA UvrABC system protein A (Gene Name=uvrA)

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