Structure of PDB 3p41 Chain A Binding Site BS02

Receptor Information

>3p41 Chain A (length=283) Species: 220664 (Pseudomonas protegens Pf-5)

HHHSLTAYQASSQARVDAAMHTLFTAPSPELARLYEAMRYSVMNGGKRVR
PLLAYAACEALGGKPEQANGAACAVELIHAYSLVHDDLPAMDDDDLRRGQ
PTTHKAFDEACAILAGDGLQSLAFSALLDPALSDASAEIRLRMVTTLAQA
AGPAGMVGGQAIDLGSVGLKLDQQALEYMHRHKTGALIEASVILGALASG
RAEKGELKALQTYAQAIGLAFQVQDDILDVESDTATPTYPALLGLAAAKE
YALELRDQALHALRPFDAAAEPLRELARYIVER

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 3p41 Chain A Residue 298

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3p41 Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily.
• Resolution: 1.76 Å
• Binding residue (original residue number in PDB): D83 D89
• Binding residue (residue number reindexed from 1): D86 D92
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 2.5.1.10: (2E,6E)-farnesyl diphosphate synthase.

Gene Ontology

Molecular Function

• GO:0004337 geranyltranstransferase activity
• GO:0004659 prenyltransferase activity
• GO:0016740 transferase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0008299 isoprenoid biosynthetic process

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:3p41, PDBe:3p41, PDBj:3p41
• PDBsum: 3p41
• PubMed: 23493556
• UniProt: Q4K5A6