Structure of PDB 3p35 Chain A Binding Site BS02

Receptor Information
>3p35 Chain A (length=217) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKY
GLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNS
LMKKITLLKYFRNYMSEHLLKAGANITPRRLPYLRTWFRTRSAIILHLSN
GSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELA
SRLRYARTMVDKLLSSR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3p35 From crystal packing to molecular recognition: prediction and discovery of a binding site on the surface of polo-like kinase 1
Resolution2.09 Å
Binding residue
(original residue number in PDB)
E460 Y462
Binding residue
(residue number reindexed from 1)
E89 Y91
Enzymatic activity
Enzyme Commision number 2.7.11.21: polo kinase.
External links
PDB RCSB:3p35, PDBe:3p35, PDBj:3p35
PDBsum3p35
PubMed21472932
UniProtP53350|PLK1_HUMAN Serine/threonine-protein kinase PLK1 (Gene Name=PLK1)

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