Structure of PDB 3oor Chain A Binding Site BS02

Receptor Information
>3oor Chain A (length=223) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NIKKNQVMNLGPNSKLLKEYKSQLIELNIEQFEAGIGLILGDAYIRSRDE
GKTYCMQFEWKNKAYMDHVCLLYDQWVLSPPHKRERVNHLGNLVITWTAQ
TFKHQAFNKLANLFIVNNKKTIPNNLVENYLTPMSLAYWFMDDGGKWDYN
KNSTNKSIVLNTQSFTFEEVEYLVKGLRNKFQLNCYVKINKNKPIIYIDS
MSYLIFYNLIKPYLIPQMMYKLP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3oor Evolution of I-SceI Homing Endonucleases with Increased DNA Recognition Site Specificity.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		P14 N15 L80 S81 R86 R88 F104 K105 D144 Y151 N152 N163 Q165 S166 K193 K195 Y222
Binding residue
(residue number reindexed from 1)		P12 N13 L78 S79 R84 R86 F102 K103 D142 Y149 N150 N161 Q163 S164 K191 K193 Y220
Binding affinityPDBbind-CN: Kd=8.2nM
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
Biological Process
GO:0006314 intron homing
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0005739 mitochondrion

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3oor, PDBe:3oor, PDBj:3oor
PDBsum3oor
PubMed21029741
UniProtP03882|SCE1_YEAST Intron-encoded endonuclease I-SceI (Gene Name=SCEI)

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