Structure of PDB 3oi7 Chain A Binding Site BS02

Receptor Information

>3oi7 Chain A (length=260) Species: 4932 (Saccharomyces cerevisiae)

LTPRCIIVRAGQTEWSKSGQYTGLTDLPLTPYGEGQMLRTGESVFRNNQF
LNPDNITYIFTSPRLRARQTVDLVLKPLSDEQRAKIRVVVDDDLREWEYG
DYEGMLTREIIELRKSRGLDKERPWNIWRDGCENGETTQQIGLRLSRAIA
RIQNLHRKHQSEGRASDIMVFAHGHALRYFAAIWFGLGVQKKCETIEEIQ
NVKSYDDDTVPYVKLESYRHLVDNPCFLLDAGGIGVLSYAHHNIDEPALE
LAGPFVSPPE

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 3oi7 Chain A Residue 311

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3oi7 Riboneogenesis in yeast.
• Resolution: 2.4 Å
• Binding residue (original residue number in PDB): T16 T25 R69
• Binding residue (residue number reindexed from 1): T13 T22 R66
• Annotation score: 1

Enzymatic activity

• Catalytic site (original residue number in PDB): A13 R69 E99
• Catalytic site (residue number reindexed from 1): A10 R66 E96
• Enzyme Commision number: 3.1.3.37: sedoheptulose-bisphosphatase.

Gene Ontology

Molecular Function

• GO:0016491 oxidoreductase activity
• GO:0016787 hydrolase activity
• GO:0050278 sedoheptulose-bisphosphatase activity

Biological Process

• GO:0046390 ribose phosphate biosynthetic process

Cellular Component

• GO:0005634 nucleus
• GO:0005737 cytoplasm

External links

• PDB: RCSB:3oi7, PDBe:3oi7, PDBj:3oi7
• PDBsum: 3oi7
• PubMed: 21663798
• UniProt: P36136|SHB17_YEAST Sedoheptulose 1,7-bisphosphatase (Gene Name=SHB17)