Structure of PDB 3oha Chain A Binding Site BS02

Receptor Information
>3oha Chain A (length=516) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GDPHMSKFTWKELIQLGSPSKAYESSLACIAHIDMNAFFAQVEQMRCGLS
KEDPVVCVQWNSIIAVSYAARKYGISRMDTIQEALKKCSNLIPIHTAVFK
KGEDFWQYHDGCGSWVQDPAKQISVEDHKVSLEPYRRESRKALAIFKWAC
DLVERASIDEVFLDLGRICFNMLMFDNEYELTGDLKLKDALSNIREAFIG
GNYDINSHLPLIPEKIKSLKFEGDVFNPEGRDLITDWDDVILALGSQVCK
GIRDSIKDILGYTTSCGLSSTKNVCKLASNYKKPDAQTIVKNDCLLDFLD
CGKFEITSFWTLGGVLGKELIDVLDLPHENSIKHIRETWPDNAGQLKEFL
DAKVKQSDYDRSTSNIDPLKTADLAEKLFKLSRGRYGLPLSSRPVVKSMM
SNKNLRGKSCNSIVDCISWLEVFCAELTSRIQDLEQEYNKIVIPRTVSIS
LKTKSYEVYRKSGPVAYKGINFQSHELLKVGIKFVTDLDIKGKNKSYYPL
TKLSMTITNFDIIDLQ
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3oha Structural basis for error-free replication of oxidatively damaged DNA by yeast DNA polymerase eta.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		Q55 W56 R73 M74 K125 V126 R132 R389 S394 M395 M396 N398 N400 R426
Binding residue
(residue number reindexed from 1)		Q59 W60 R77 M78 K129 V130 R136 R393 S398 M399 M400 N402 N404 R430
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003684 damaged DNA binding
Biological Process
GO:0006281 DNA repair

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3oha, PDBe:3oha, PDBj:3oha
PDBsum3oha
PubMed21070945
UniProtQ04049|POLH_YEAST DNA polymerase eta (Gene Name=RAD30)

[Back to BioLiP]