Structure of PDB 3ncu Chain A Binding Site BS02
Receptor Information
>3ncu Chain A (length=120) Species:
9606
(Homo sapiens) [
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ENKKLLCRKCKALACYTADVRVIEECHYTVLGDAFKECFVSRPHPKPKQF
SSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATGVQT
LYSKWKDFHFEKIPFDPAEM
Ligand information
>3ncu Chain D (length=12) [
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gacgcuagcguc
............
Receptor-Ligand Complex Structure
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PDB
3ncu
Structural and functional insights into 5'-ppp RNA pattern recognition by the innate immune receptor RIG-I.
Resolution
2.55 Å
Binding residue
(original residue number in PDB)
K849 F853 S854
Binding residue
(residue number reindexed from 1)
K46 F50 S51
Binding affinity
PDBbind-CN
: Kd=29.2nM
Enzymatic activity
Enzyme Commision number
3.6.4.13
: RNA helicase.
External links
PDB
RCSB:3ncu
,
PDBe:3ncu
,
PDBj:3ncu
PDBsum
3ncu
PubMed
20581823
UniProt
O95786
|RIGI_HUMAN Antiviral innate immune response receptor RIG-I (Gene Name=RIGI)
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