Structure of PDB 3n9o Chain A Binding Site BS02

Receptor Information

>3n9o Chain A (length=483) Species: 6239 (Caenorhabditis elegans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

PKESDRCGGCGKFTHEDKKNDFQWIGCDSCQTWYHFLCSGLEQFEYYLYE
KFFCPKCVPHTGHSIRYKVVAPHRYRWYSPNEKHLGIEVGSKTWIEDFIT
RENTVPSPTDDEVCIVEDGYEFRREFEKLGGADNWGKVFMVKDMDGLNMT
MPKPGFDLEDVVKIMGSDYEVDTIDVYNQSTYSMKLDTFRKLFRDTKNRP
LLYNFLSLEFSDNNEMKEIAKPPRFVQEISMVNRLWPDVSGAEYIKLLQR
EEYLPEDQRPKVEQFCLAGMAGSYTDFHVDFGGSSVYYHILKGEKIFYIA
APTEQNFAAYQAHETSPDTTTWFGDIANGAVKRVVIKEGQTLLIPAGWIH
AVLTPVDSLVFGGNFLHLGNLEMQMRVYHLENAIRKEIRSEEKFYFPNFE
LLHWMYMRNVLLEKITEANQEGSDMREQEKNIWTASQIMKAEMERWMDRE
LRLGPEILPTDDKNKIMISVRKQIEIQTKIQNA

Ligand information

>3n9o Chain C (length=8) Species: 6239 (Caenorhabditis elegans) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

KQTARKST

Receptor-Ligand Complex Structure

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Structure summary

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PDB	3n9o Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans
Resolution	2.309 Å
Binding residue (original residue number in PDB)	D389 I391 Q396 S397 T398 S424 V479 F482 F498 E531 S533 G580 N581 S607 K610 F611 Y612
Binding residue (residue number reindexed from 1)	D172 I174 Q179 S180 T181 S207 V262 F265 F281 E314 S316 G363 N364 S390 K393 F394 Y395

Enzymatic activity

Enzyme Commision number

1.14.11.-

External links

PDB	RCSB:3n9o, PDBe:3n9o, PDBj:3n9o
PDBsum	3n9o
PubMed	20567261
UniProt	Q9GYI0\|KDM7_CAEEL Lysine-specific demethylase 7 homolog (Gene Name=jmjd-1.2)

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