Structure of PDB 3m4a Chain A Binding Site BS02
Receptor Information
>3m4a Chain A (length=304) Species:
1299
(Deinococcus radiodurans) [
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PSRTELLARRARIARLAVPPAYQDVYVSPDAENELQAFGRDAARLQYRYH
PDFVALKKWQRLTRFAGALPTLKVATTADLRASGLPPRKVMALMTRLLHV
ARFRVGSDIYARQHKTYGLSTLRQRHVVVDGNTVTFRFKGKHGVSQHKAT
SDRTLAANMQKLLDLPGPWLFQTVDAGGERRRIHSTELNAYLREVIGPFT
AKDFRTWGGTLLAAEYLAQQGTESSERQAKKVLVDCVKFVADDLGNTPAV
TRGSYICPVIFDRYLDGKVLDDYEPRTERQEAELEGLTRSEGALKRMLES
ERTL
Ligand information
>3m4a Chain E (length=12) [
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gcgcccttattc
Receptor-Ligand Complex Structure
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PDB
3m4a
Crystal structure of a bacterial topoisomerase IB in complex with DNA reveals a secondary DNA binding site.
Resolution
1.65 Å
Binding residue
(original residue number in PDB)
P2 A111 R114
Binding residue
(residue number reindexed from 1)
P1 A78 R81
Enzymatic activity
Enzyme Commision number
5.6.2.1
: DNA topoisomerase.
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0003916
DNA topoisomerase activity
GO:0003917
DNA topoisomerase type I (single strand cut, ATP-independent) activity
Biological Process
GO:0006265
DNA topological change
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Molecular Function
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Biological Process
External links
PDB
RCSB:3m4a
,
PDBe:3m4a
,
PDBj:3m4a
PDBsum
3m4a
PubMed
20541510
UniProt
Q9RWH8
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