Structure of PDB 3m3a Chain A Binding Site BS02

Receptor Information

>3m3a Chain A (length=153) Species: 9755 (Physeter catodon)

VLSEGEWQLVLHVWAKVEADVAGHGQDIHIRLFKSHPETLEKHDRFKHLK
TEAEMKASEDLKKHGVTELTALGAILKKKGHHEAELKPLAQSHATKHKIP
IKYLEFESEAIIHVLHSRHPGDFGADAQGAMNKALELFRKDIAAKYKELG
YQG

Ligand information

• Ligand ID: CU
• InChI: InChI=1S/Cu/q+2
• InChIKey: JPVYNHNXODAKFH-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Cu+2]
  CACTVS 3.341: [Cu++]
• Formula: Cu
• Name: COPPER (II) ION
• DrugBank: DB14552
• PDB chain: 3m3a Chain A Residue 156

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3m3a Roles of glutamates and metal ions in a rationally designed nitric oxide reductase based on myoglobin.
• Resolution: 1.37 Å
• Binding residue (original residue number in PDB): H29 H43 H64 E68
• Binding residue (residue number reindexed from 1): H29 H43 H64 E68
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 1.11.1.-
  1.7.-.-

Gene Ontology

Molecular Function

• GO:0004601 peroxidase activity
• GO:0005344 oxygen carrier activity
• GO:0016491 oxidoreductase activity
• GO:0019825 oxygen binding
• GO:0020037 heme binding
• GO:0046872 metal ion binding
• GO:0098809 nitrite reductase activity

Biological Process

• GO:0015671 oxygen transport
• GO:0019430 removal of superoxide radicals

Cellular Component

• GO:0005737 cytoplasm
• GO:0016528 sarcoplasm
• GO:0070062 extracellular exosome

External links

• PDB: RCSB:3m3a, PDBe:3m3a, PDBj:3m3a
• PDBsum: 3m3a
• PubMed: 20421510
• UniProt: P02185|MYG_PHYMC Myoglobin (Gene Name=MB)