Structure of PDB 3m1i Chain A Binding Site BS02

Receptor Information
>3m1i Chain A (length=200) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VPTFKLVLVGDGGTGKTTFVKRHLTGEFEKKYIATIGVEVHPLSFYTNFG
EIKFDVWDTAGLEKFGGLRDGYYINAQCAIIMFDVTSRITYKNVPNWHRD
LVRVCENIPIVLCGNKVDVKERKVKAKTITFHRKKNLQYYDISAKSNYNF
EKPFLWLARKLAGNPQLEFVASPALAPPEQQYQQEMEQATALPLPDEDDA
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain3m1i Chain A Residue 1178 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3m1i An allosteric mechanism to displace nuclear export cargo from CRM1 and RanGTP by RanBP1
Resolution2.0 Å
Binding residue
(original residue number in PDB)		T26 T44
Binding residue
(residue number reindexed from 1)		T17 T35
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0000054 ribosomal subunit export from nucleus
GO:0000467 exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006606 protein import into nucleus
GO:0006913 nucleocytoplasmic transport
GO:0006997 nucleus organization
GO:0015031 protein transport
GO:0016973 poly(A)+ mRNA export from nucleus
GO:0046822 regulation of nucleocytoplasmic transport
GO:1901987 regulation of cell cycle phase transition
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3m1i, PDBe:3m1i, PDBj:3m1i
PDBsum3m1i
PubMed20485264
UniProtP32835|GSP1_YEAST GTP-binding nuclear protein GSP1/CNR1 (Gene Name=GSP1)

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