Structure of PDB 3lw6 Chain A Binding Site BS02

Receptor Information
>3lw6 Chain A (length=241) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GASVHKMALLVPFRDRFEELLQFVPHMTAFLKRQGVAHHIFVLNQVDRFR
FNRASLINVGFQFASDVYDYIAMHDVDLLPLNDNLLYEYPSSLGPLHIAG
PKLHPKYHYDNFVGGILLVRREHFKQMNGMSNQYWGWGLEDDEFFVRIRD
AGLQVTRPQNIKTGTNDTFSHIHNRYHRKRDTQKCFNQKEMTRKRDHKTG
LDNVKYKILKVHEMLIDQVPVTILNILLDCDVNKTPWCDCS
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain3lw6 Chain A Residue 314 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3lw6 Crystal structure of the catalytic domain of Drosophila beta1,4-Galactosyltransferase-7.
Resolution1.81 Å
Binding residue
(original residue number in PDB)		D147 H241 H243
Binding residue
(residue number reindexed from 1)		D77 H171 H173
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) D145 D147 W207 E210 D211 T238 H241 H243
Catalytic site (residue number reindexed from 1) D75 D77 W137 E140 D141 T168 H171 H173
Enzyme Commision number 2.4.1.133: xylosylprotein 4-beta-galactosyltransferase.
Gene Ontology
Molecular Function
GO:0016757 glycosyltransferase activity
Biological Process
GO:0005975 carbohydrate metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3lw6, PDBe:3lw6, PDBj:3lw6
PDBsum3lw6
PubMed20236943
UniProtQ9VBZ9|B4GT7_DROME Beta-1,4-galactosyltransferase 7 (Gene Name=beta4GalT7)

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