Structure of PDB 3lo1 Chain A Binding Site BS02

Receptor Information
>3lo1 Chain A (length=30) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ACYCRIPACIAGERRAGTCIYQGRLWAFCC
Ligand information
Ligand IDAZI
InChIInChI=1S/N3/c1-3-2/q-1
InChIKeyIVRMZWNICZWHMI-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[N-]=[N+]=[N-]
FormulaN3
NameAZIDE ION
ChEMBLCHEMBL79455
DrugBank
ZINC
PDB chain3lo1 Chain A Residue 31 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3lo1 Trp-26 imparts functional versatility to human alpha-defensin HNP1.
Resolution1.6 Å
Binding residue
(original residue number in PDB)		A1 E13 C30
Binding residue
(residue number reindexed from 1)		A1 E13 C30
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006952 defense response
Cellular Component
GO:0005576 extracellular region

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3lo1, PDBe:3lo1, PDBj:3lo1
PDBsum3lo1
PubMed20220136
UniProtP59665|DEF1_HUMAN Neutrophil defensin 1 (Gene Name=DEFA1)

[Back to BioLiP]