Structure of PDB 3l3q Chain A Binding Site BS02
Receptor Information
>3l3q Chain A (length=427) Species:
10090
(Mus musculus) [
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QGTVNWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGL
IPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISL
LASPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLST
LACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLAD
SCWAISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNI
VTGTDEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQI
QQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCG
IIEPLMNLLSAKDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGL
DKIEALQRHENESVYKASLNLIEKYFS
Ligand information
>3l3q Chain C (length=6) [
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KKRREA
Receptor-Ligand Complex Structure
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PDB
3l3q
Probing the specificity of binding to the major nuclear localization sequence-binding site of importin-alpha using oriented peptide library screening.
Resolution
2.3 Å
Binding residue
(original residue number in PDB)
G281 N283 V321 T322 T328 W357 S360 N361 A364 E396 W399
Binding residue
(residue number reindexed from 1)
G211 N213 V251 T252 T258 W287 S290 N291 A294 E326 W329
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3l3q
,
PDBe:3l3q
,
PDBj:3l3q
PDBsum
3l3q
PubMed
20406804
UniProt
P52293
|IMA1_MOUSE Importin subunit alpha-1 (Gene Name=Kpna2)
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