Structure of PDB 3l2w Chain A Binding Site BS02
Receptor Information
>3l2w Chain A (length=365) Species:
11963
(Human spumaretrovirus) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
AELDQLLQGHYIKGYPKQYTYFLEDGKVKVSRPEGVKIIPPQSDRQKIVL
QAHNLAHTGREATLLKIANLYWWPNMRKDVVKQLGRCQQCLITNASNKAS
GPILRPDRPQKPFDKFFIDYIGPLPPSQGYLYVLVVVDGMTGFTWLYPTK
APSTSATVKSLNVLTSIAIPKVIHSDQGAAFTSSTFAEWAKERGIHLEFS
TPYHPQSSGKVERKNSDIKRLLTKLLVGRPTKWYDLLPVVQLALNNTYSP
VLKYTPHQLLFGIDSNTPFANQDTLDLTREEELSLLQEIRTSLYHPSTPP
ASSRSWSPVVGQLVQERVARPASLRPRWHKPSTVLKVLNPRTVVILDHLG
NNRTVSIDNLKPTSH
Ligand information
>3l2w Chain D (length=17) [
Search DNA sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
tacaaaattccatgaca
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
3l2w
Retroviral intasome assembly and inhibition of DNA strand transfer
Resolution
3.2 Å
Binding residue
(original residue number in PDB)
E221 R222 S225 K228 K262
Binding residue
(residue number reindexed from 1)
E212 R213 S216 K219 K253
Enzymatic activity
Enzyme Commision number
2.7.7.-
2.7.7.49
: RNA-directed DNA polymerase.
2.7.7.7
: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4
: ribonuclease H.
3.4.23.-
Gene Ontology
Molecular Function
GO:0003676
nucleic acid binding
Biological Process
GO:0015074
DNA integration
View graph for
Molecular Function
View graph for
Biological Process
External links
PDB
RCSB:3l2w
,
PDBe:3l2w
,
PDBj:3l2w
PDBsum
3l2w
PubMed
20118915
UniProt
P14350
|POL_FOAMV Pro-Pol polyprotein (Gene Name=pol)
[
Back to BioLiP
]