Structure of PDB 3l1p Chain A Binding Site BS02
Receptor Information
>3l1p Chain A (length=147) Species:
10090
(Mus musculus) [
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DMKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTISRF
EALQLSLKNMSKLRPLLEKWVEEADNNENLQEISKSVQARKRKRTSIENR
VRWSLETMFLKSPKPSLQQITHIANQLGLEKDVVRVWFSNRRQKGKR
Ligand information
>3l1p Chain M (length=23) [
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atccatttgcctttcaaatgtgg
Receptor-Ligand Complex Structure
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PDB
3l1p
A unique Oct4 interface is crucial for reprogramming to pluripotency
Resolution
2.8 Å
Binding residue
(original residue number in PDB)
R20 T26 Q27 Q44 T45 R49 R97 T98 I100 V139 N143
Binding residue
(residue number reindexed from 1)
R20 T26 Q27 Q44 T45 R49 R94 T95 I97 V136 N140
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0000981
DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677
DNA binding
GO:0003700
DNA-binding transcription factor activity
Biological Process
GO:0006355
regulation of DNA-templated transcription
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Molecular Function
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Biological Process
External links
PDB
RCSB:3l1p
,
PDBe:3l1p
,
PDBj:3l1p
PDBsum
3l1p
PubMed
23376973
UniProt
P20263
|PO5F1_MOUSE POU domain, class 5, transcription factor 1 (Gene Name=Pou5f1)
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