Structure of PDB 3kqi Chain A Binding Site BS02

Receptor Information
>3kqi Chain A (length=71) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSMATVPVYCVCRLPYDVTRFMIECDACKDWFHGSCVGVEEEEAPDIDIY
HCPNCEKTHGKSTLKKKRTWH
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3kqi Chain A Residue 71 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3kqi Recognition of histone H3K4 trimethylation by the plant homeodomain of PHF2 modulates histone demethylation.
Resolution1.78 Å
Binding residue
(original residue number in PDB)		C23 C26 C50 C53
Binding residue
(residue number reindexed from 1)		C25 C28 C52 C55
Annotation score1
Enzymatic activity
Enzyme Commision number 1.14.11.-
Gene Ontology
Cellular Component
GO:0048188 Set1C/COMPASS complex

View graph for
Cellular Component
External links
PDB RCSB:3kqi, PDBe:3kqi, PDBj:3kqi
PDBsum3kqi
PubMed20129925
UniProtO75151|PHF2_HUMAN Lysine-specific demethylase PHF2 (Gene Name=PHF2)

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