Structure of PDB 3kko Chain A Binding Site BS02

Receptor Information
>3kko Chain A (length=169) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NLPTYKLVVVGDGGVGKSALTIQFFQKIFVDEYDPTIEDSYRKHTEIDNQ
WAILDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQL
ILRVKDRESFPMILVANKVDLMHLRKVTRDQGKEMATKYNIPYIETSAKD
PPLNVDKTFHDLVRVIRQQ
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain3kko Chain A Residue 180 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3kko Structural basis for conformational dynamics of GTP-bound Ras protein
Resolution1.9 Å
Binding residue
(original residue number in PDB)		S27 T45
Binding residue
(residue number reindexed from 1)		S18 T36
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3kko, PDBe:3kko, PDBj:3kko
PDBsum3kko
PubMed20479006
UniProtO08989|RASM_MOUSE Ras-related protein M-Ras (Gene Name=Mras)

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