Structure of PDB 3k5x Chain A Binding Site BS02

Receptor Information

>3k5x Chain A (length=391) Species: 1902 (Streptomyces coelicolor) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MTSLEKARELLREFPVVDGHNDLPWALREQVRYDLDARDIAADQSAHLHT
DLARLRSGGVGAQYWSVYVRSDLPGAVTATLEQIDCVRRLIDRHPGELRA
ALTAADMEAARAEGRIASLMGAEGGHSIDNSLATLRALYALGVRYMTLTH
NDNNAWADSATDEPGVGGLSAFGREVVREMNREGMLVDLSHVAATTMRDA
LDTSTAPVIFSHSSSRAVCDHPRNIPDDVLERLSANGGMAMVTFVPKFVL
QAAVDWTAEADDNMRAHGFHHLDSSPEAMKVHAAFEERVPRPVATVSTVA
DHLDHMREVAGVDHLGIGGDYDGTPFTPDGLGDVSGYPNLIAELLDRGWS
QSDLAKLTWKNAVRVLDAAEDVSRGLRAARGPSNATIEQLD

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

3k5x Chain A Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	3k5x Structure, mechanism, and substrate profile for Sco3058: the closest bacterial homologue to human renal dipeptidase .
Resolution	1.4 Å
Binding residue (original residue number in PDB)	H20 D22 E123
Binding residue (residue number reindexed from 1)	H20 D22 E123
Annotation score	4

Enzymatic activity

Catalytic site (original residue number in PDB)	H20 D22 E123 H150 H191 H212 D320
Catalytic site (residue number reindexed from 1)	H20 D22 E123 H150 H191 H212 D320
Enzyme Commision number	?

Gene Ontology

	Molecular Function
GO:0046872	metal ion binding
GO:0070573	metallodipeptidase activity

	Biological Process
GO:0006508	proteolysis

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Molecular Function

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Biological Process

External links

PDB	RCSB:3k5x, PDBe:3k5x, PDBj:3k5x
PDBsum	3k5x
PubMed	20000809
UniProt	Q93J45

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