Structure of PDB 3k5n Chain A Binding Site BS02

Receptor Information
>3k5n Chain A (length=759) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MAQAGFILTRHWRDTPQGTEVSFWLATDNGPLQVTLAPQESVAFIPADQV
PRAQHILQGEQGFRLTPLALKDFHRQPVYGLYCRAHRQLMNYEKRLREGG
VTVYEADVRPPERYLMERFITSPVWVEGDMHNGTIVNARLKPHPDYRPPL
KWVSIDIETTRHGELYCIGLEGCGQRIVYMLGPENGDASSLDFELEYVAS
RPQLLEKLNAWFANYDPDVIIGWNVVQFDLRMLQKHAERYRLPLRLGRDN
SELEWFFAQAKGRLIIDGIEALKSAFWNFSSFSLETVAQELLGEGWDRMD
EIDRRFAEDKPALATYNLKNCELVTQIFHKTEIMPFLLERATVNGLPVDR
HGGSVAAFGHLYFPRMHRAGYVAPNLGEVPPHASPGGYVMDSRPGLYDSV
LVLDYKSLYPSIIRTFLIDPVGLVEGMAQPDPEHSTEGFLDAWFSREKHC
LPEIVTNIWHGRDEAKRQGNKPLSQALKIIMNAFYGVLGTTACRFFDPRL
ASSITMRGHQIMRQTKALIEAQGYDVIYGDTDSTFVWLKGAHSEEEAAKI
GRALVQHVNAWWAETLQKQRLTSALELEYETHFCRFLMPTKRYAGLIQEG
DKQRMVFKGLETVRTDWTPLAQQFQQELYLRIFRNEPYQEYVRETIDKLM
AGELDARLVYRKRLRRPLSEYQRNVPPHVRAARLADEENQKRGRPLQYQN
RGTIKYVWTTNGPEPLDYQRSPLDYEHYLTRQLQPVAEGILPFIEDNFAT
LMTGQLGLF
Ligand information
Receptor-Ligand Complex Structure
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PDB3k5n Structural insight into translesion synthesis by DNA Pol II.
Resolution3.15 Å
Binding residue
(original residue number in PDB)		V637 R638 T639 K686 R687 R689 R690 Y695 R697
Binding residue
(residue number reindexed from 1)		V613 R614 T615 K662 R663 R665 R666 Y671 R673
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0008296 3'-5'-DNA exonuclease activity
Biological Process
GO:0006261 DNA-templated DNA replication
GO:0006281 DNA repair
GO:0006974 DNA damage response
GO:0009432 SOS response
GO:0045004 DNA replication proofreading
GO:0071897 DNA biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3k5n, PDBe:3k5n, PDBj:3k5n
PDBsum3k5n
PubMed20064374
UniProtP21189|DPO2_ECOLI DNA polymerase II (Gene Name=polB)

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