Structure of PDB 3k57 Chain A Binding Site BS02

Receptor Information
>3k57 Chain A (length=782) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PHMAQAGFILTRHWRDTPQGTEVSFWLATDNGPLQVTLAPQESVAFIPAD
QVPRAQHILQGEQGFRLTPLALKDFHRQPVYGLYCRAHRQLMNYEKRLRE
GGVTVYEADVRPPERYLMERFITSPVWVEGDMHNGTIVNARLKPHPDYRP
PLKWVSIDIETTRHGELYCIGLEGCGQRIVYMLGPENGDASSLDFELEYV
ASRPQLLEKLNAWFANYDPDVIIGWNVVQFDLRMLQKHAERYRLPLRLGR
DNSELEWREHGFKNGVFFAQAKGRLIIDGIEALKSAFWNFSSFSLETVAQ
ELLGEGKSIDNPWDRMDEIDRRFAEDKPALATYNLKNCELVTQIFHKTEI
MPFLLERATVNGLPVDRHGGSVAAFGHLYFPRMHRAGYVAPNLGEVPPHA
SPGGYVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLVEGMAQPDPE
HSTEGFLDAWFSREKHCLPEIVTNIWHGRDEAKRQGNKPLSQALKIIMNA
FYGVLGTTACRFFDPRLASSITMRGHQIMRQTKALIEAQGYDVIYGDTDS
TFVWLKGAHSEEEAAKIGRALVQHVNAWWAETLQKQRLTSALELEYETHF
CRFLMPTIRGADTGSKKRYAGLIQEGDKQRMVFKGLETVRTDWTPLAQQF
QQELYLRIFRNEPYQEYVRETIDKLMAGELDARLVYRKRLRRPLSEYQRN
VPPHVRAARLADEENQKRGRPLQYQNRGTIKYVWTTNGPEPLDYQRSPLD
YEHYLTRQLQPVAEGILPFIEDNFATLMTGQL
Ligand information
Receptor-Ligand Complex Structure
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PDB3k57 Structural insight into translesion synthesis by DNA Pol II
Resolution2.08 Å
Binding residue
(original residue number in PDB)		K615 Y617 K632 G633 V637 R638 T639 D640 K686 R687 R689 Y695 H702
Binding residue
(residue number reindexed from 1)		K617 Y619 K634 G635 V639 R640 T641 D642 K688 R689 R691 Y697 H704
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0008296 3'-5'-DNA exonuclease activity
Biological Process
GO:0006261 DNA-templated DNA replication
GO:0006281 DNA repair
GO:0006974 DNA damage response
GO:0009432 SOS response
GO:0045004 DNA replication proofreading
GO:0071897 DNA biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3k57, PDBe:3k57, PDBj:3k57
PDBsum3k57
PubMed20064374
UniProtP21189|DPO2_ECOLI DNA polymerase II (Gene Name=polB)

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