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Receptor Information

>3k4x Chain A (length=758) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

LEAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLE
IGVEAFQEYRCDHPVTLGMDLTSLSKILRCGNNTDTLTLIADNTPDSIIL
LFEDTKKDRIAEYSLKLMDIDADFLKIEELQYDSTLSLPSSEFSKIVRDL
SQLSDSINIMITKETIKFVADGDIGSGSVIIKPFVDMEHPETSIKLEMDQ
PVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFDLKSGFLQFFLA
PKLEAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVS
LEIGVEAFQEYRCDHPVTLGMDLTSLSKILRCGNNTDTLTLIADNTPDSI
ILLFEDTKKDRIAEYSLKLMDIDADFLKIEELQYDSTLSLPSSEFSKIVR
DLSQLSDSINIMITKETIKFVADGDIGSGSVIIKPFVDMEHPETSIKLEM
DQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFDLKSGFLQFF
LAPKFNLEAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVDDSRV
LLVSLEIGVEAFQEYRCDHPVTLGMDLTSLSKILRCGNNTDTLTLIADNT
PDSIILLFEDTKKDRIAEYSLKLMDIDADFLKIEELQYDSTLSLPSSEFS
KIVRDLSQLSDSINIMITKETIKFVADGDIGSGSVIIKPFVDMEHPETSI
KLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFDLKSGF
LQFFLAPK

Receptor-Ligand Complex Structure

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Structure summary

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PDB	3k4x Analysis of the role of PCNA-DNA contacts during clamp loading.
Resolution	2.98 Å
Binding residue (original residue number in PDB)	H190 T373 K374
Binding residue (residue number reindexed from 1)	H189 T357 K358

Enzyme Commision number

	Molecular Function
GO:0003677	DNA binding
GO:0030337	DNA polymerase processivity factor activity

	Biological Process
GO:0006260	DNA replication
GO:0006272	leading strand elongation
GO:0006275	regulation of DNA replication
GO:0006298	mismatch repair
GO:0019985	translesion synthesis

	Cellular Component
GO:0005634	nucleus
GO:0043626	PCNA complex

PDB	RCSB:3k4x, PDBe:3k4x, PDBj:3k4x
PDBsum	3k4x
PubMed	20113510
UniProt	A6ZL36

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Structure of PDB 3k4x Chain A Binding Site BS02