Structure of PDB 3k23 Chain A Binding Site BS02
Receptor Information
>3k23 Chain A (length=245) Species:
9606
(Homo sapiens) [
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LPQLTPTLVSLLEVIEPEVLYAGYDSVPDSTWRIMTTLNMLGGRQVIAAV
KWAKAIPGFRNLHLDDQMTLLQYSWMYLMAFALGWRSYRQSSANLLCFAP
DLIINEQGMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGL
KSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVE
NLLNYCFQTFLDKMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQ
Ligand information
>3k23 Chain E (length=10) Species:
9606
(Homo sapiens) [
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NALLRYLLDK
Receptor-Ligand Complex Structure
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PDB
3k23
Design and x-ray crystal structures of high-potency nonsteroidal glucocorticoid agonists exploiting a novel binding site on the receptor.
Resolution
3.0 Å
Binding residue
(original residue number in PDB)
Y648 E652 K720
Binding residue
(residue number reindexed from 1)
Y118 E122 K190
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3k23
,
PDBe:3k23
,
PDBj:3k23
PDBsum
3k23
PubMed
19822747
UniProt
P04150
|GCR_HUMAN Glucocorticoid receptor (Gene Name=NR3C1)
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