Structure of PDB 3j2q Chain A Binding Site BS02

Receptor Information
>3j2q Chain A (length=630) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ATRRYYLGAVELSWDYVVYKKTLFVEFTDHLFNIAKPRPPWMGLLGPTIQ
AEVYDTVVITLKNMASHPVSLHAVGVSYWKASEGAEYDDQTSQREKEDDK
VFPGGSHTYVWQVLKENGPMASDPLCLTYSYLSHVDLVKDLNSGLIGALL
VCREGSLAKEKTQTLHKFILLFAVFDEGKSWHSSARAWPKMHTVNGYVNR
SLPGLIGCHRKSVYWHVIGMGTTPEVHSIFLEGHTFLVRNHRQASLEISP
ITFLTAQTLLMDLGQFLLFCHISSHQHDGMEAYVKVDSCPEEPKHPKTWV
HYIAAEEEDWDYAPLVLAPDDRSYKSQYLNNGPQRIGRKYKKVRFMAYTD
ETFKTREAIQHESGILGPLLYGEVGDTLLIIFKNQASRPYNIYPHGITDV
RPLYSRRLPKGVKHLKDFPILPGEIFKYKWTVTVEDGPTKSDPRCLTRYY
SSFVNMERDLASGLIGPLLICYKESVDQRGNQIMSDKRNVILFSVFDENR
SWYLTENIQRFLPNPAGVQLEDPEFQASNIMHSINGYVFDSLQLSVCLHE
VAYWYILSIGAQTDFLSVFFSGYTFKHKMVYEDTLTLFPFSGETVFMSME
NPGLWILGCHNSDFRNRGMTALLKVSSCDK
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain3j2q Chain A Residue 804 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3j2q Domain organization of membrane-bound factor VIII.
Resolution15.0 Å
Binding residue
(original residue number in PDB)		K107 D116 E122 D125 D126
Binding residue
(residue number reindexed from 1)		K80 D89 E95 D98 D99
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005507 copper ion binding

View graph for
Molecular Function
External links
PDB RCSB:3j2q, PDBe:3j2q, PDBj:3j2q
PDBsum3j2q
PubMed23616213
UniProtP00451|FA8_HUMAN Coagulation factor VIII (Gene Name=F8)

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