Structure of PDB 3io3 Chain A Binding Site BS02

Receptor Information
>3io3 Chain A (length=230) Species: 4959 (Debaryomyces hansenii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DLELEPTLESIVQHDSLKWIFVGGKGGVGKTTTSSSVAVQLALAQPNEQF
LLISTDPAHNLSDAFCQKFGKDARKVEGLPNLSCMEIDPYKTIIFDTAPT
GHTLRFLQSEVNEQFTNPELTTFICVCISEFLSLYETERMIQELMSYNMD
VNSIVVNQLLFAECKRCESRWKMQKKYLDQMGELYEDYHLVKMPLLGCEI
RGVENLKKFSKFLLKPYDPKADSDIVFDLE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3io3 Chain A Residue 349 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3io3 The crystal structures of yeast Get3 suggest a mechanism for tail-anchored protein membrane insertion
Resolution1.8 Å
Binding residue
(original residue number in PDB)		C280 C283
Binding residue
(residue number reindexed from 1)		C164 C167
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) G28 G30 K31 T32 T33 D57
Catalytic site (residue number reindexed from 1) G27 G29 K30 T31 T32 D56
Enzyme Commision number 3.6.-.-
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0046872 metal ion binding
Biological Process
GO:0006620 post-translational protein targeting to endoplasmic reticulum membrane
GO:0045048 protein insertion into ER membrane
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0043529 GET complex

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Biological Process
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Cellular Component
External links
PDB RCSB:3io3, PDBe:3io3, PDBj:3io3
PDBsum3io3
PubMed19956640
UniProtQ6BSM0|GET3_DEBHA ATPase GET3 (Gene Name=GET3)

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