Structure of PDB 3hx0 Chain A Binding Site BS02

Receptor Information
>3hx0 Chain A (length=330) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SQKATNHNLHITEKLEVLAKAYSVQGDKWRAAGYAKAINALKSFHKPVTS
YQEACSIPGIGKRMAEKIIEILESGHLRKLDHISESVPVLELFSNIWGAG
TKTAQMWYQQGFRSLEDIRSQASLTTQQAIGLKHYSDFLERMPREEATEI
EQTVQKAAQAFNSGLLCVACGSYRRGKATCGDVDVLITHPDGRSHRGIFS
RLLDSLRQEGFLTDDLVSQEENGQQQKYLGVCRLPGPGRRHRRLDIIVVP
YSEFACALLYFTGSAAFNASMRALAKTKGMSLSEHALSTAVVRNTHGAKV
GPGRVLPTPTEKDVFRLLGLPYREPAERDW
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3hx0 Scrunching During DNA Repair Synthesis
Resolution3.0 Å
Binding residue
(original residue number in PDB)		W342 G343 G345 K347 T348 D490 Y505
Binding residue
(residue number reindexed from 1)		W97 G98 G100 K102 T103 D245 Y260
Enzymatic activity
Catalytic site (original residue number in PDB) D427 D429 D490
Catalytic site (residue number reindexed from 1) D182 D184 D245
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
4.2.99.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0034061 DNA polymerase activity
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:3hx0, PDBe:3hx0, PDBj:3hx0
PDBsum3hx0
PubMed
UniProtQ9UGP5|DPOLL_HUMAN DNA polymerase lambda (Gene Name=POLL)

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