Structure of PDB 3hp6 Chain A Binding Site BS02 |
| >3hp6 Chain A (length=580) Species: 1422 (Geobacillus stearothermophilus)
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AKMAFTLADRVTEEMLADKAALVVEVVEENYHDAPIVGIAVVNEHGRFFL
RPETALADPQFVAWLGDETKKKSMFDSKRAAVALKWKGIELCGVSFDLLL
AAYLLDPAQGVDDVAAAAKMKQYEAVRPDEAVYGKGAKRAVPDEPVLAEH
LVRKAAAIWELERPFLDELRRNEQDRLLVELEQPLSSILAEMEFAGVKVD
TKRLEQMGKELAEQLGTVEQRIYELAGQEFNINSPKQLGVILFEKLQLPV
LKKTKTGYSTSADVLEKLAPYHEIVENILHYRQLGKLQSTYIEGLLKVVR
PATKKVHTIFNQALTQTGRLSSTEPNLQNIPIRLEEGRKIRQAFVPSESD
WLIFAADYSQIELRVLAHIAEDDNLMEAFRRDLDIHTKTAMDIFQVSEDE
VTPNMRRQAKAVNYGIVYGISDYGLAQNLNISRKEAAEFIERYFESFPGV
KRYMENIVQEAKQKGYVTTLLHRRRYLPDITSRNFNVRSFAERMAMNTPI
QGSAADIIKKAMIDLNARLKEERLQAHLLLQVHDELILEAPKEEMERLCR
LVPEVMEQAVTLRVPLKVDYHYGSTWYDAK |
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| PDB | 3hp6 The structure of a high fidelity DNA polymerase bound to a mismatched nucleotide reveals an "ajar" intermediate conformation in the nucleotide selection mechanism. |
| Resolution | 1.81 Å |
Binding residue
(original residue number in PDB) | N527 N529 S530 Q533 K582 S585 T586 L610 T611 Q612 T613 S617 S618 T619 E620 N622 Y710 Y714 I716 S717 Y719 G720 R771 F781 N782 R789 M790 N793 Q797 |
Binding residue
(residue number reindexed from 1) | N231 N233 S234 Q237 K286 S289 T290 L314 T315 Q316 T317 S321 S322 T323 E324 N326 Y414 Y418 I420 S421 Y423 G424 R475 F485 N486 R493 M494 N497 Q501 |
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| Enzyme Commision number |
2.7.7.7: DNA-directed DNA polymerase. |
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