Structure of PDB 3hot Chain A Binding Site BS02

Receptor Information
>3hot Chain A (length=338) Species: 7226 (Drosophila mauritiana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VPNKEQTRTVLIFCFHLKKTAAESHRMLVEAFGEQVPTVKTCERWFQRFK
SGDFDVDDKEHGKPPKRYEDAELQALLDEDDAQTQKQLAEQLEVSQQAVS
NRLREMGKIQKVGRWVPHELNERQMERRKNTCEILLSRYKRKSFLHRIVT
GDEKWIFFVNPKRKKSYVDPGQPATSTARPNRFGKKTMLCVWWDQSGVIY
YELLKPGETVNAARYQQQLINLNRALQRKRPEYQHRVIFLHDNAPSHTAR
AVRDTLETLNWEVLPHAAYSPDLAPSDYHLFASMGHALAEQRFDSYESVK
KWLDEWFAAKDDEFYWRGIHKLPERWEKCVASDGKYFE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3hot Molecular architecture of the Mos1 paired-end complex: the structural basis of DNA transposition in a eukaryote
Resolution3.25 Å
Binding residue
(original residue number in PDB)		A25 A26 R30 K44 E47 Q51 H65 K67 P68 K70 R71 V98 S99 Q101 A102 R106 R167 G175
Binding residue
(residue number reindexed from 1)		A21 A22 R26 K40 E43 Q47 H61 K63 P64 K66 R67 V94 S95 Q97 A98 R102 R163 G171
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0000014 single-stranded DNA endodeoxyribonuclease activity
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0003697 single-stranded DNA binding
GO:0004519 endonuclease activity
GO:0042800 histone H3K4 methyltransferase activity
GO:0044547 DNA topoisomerase binding
GO:0046872 metal ion binding
GO:0046975 histone H3K36 methyltransferase activity
Biological Process
GO:0000729 DNA double-strand break processing
GO:0006303 double-strand break repair via nonhomologous end joining
GO:0006310 DNA recombination
GO:0006338 chromatin remodeling
GO:0015074 DNA integration
GO:0031297 replication fork processing
GO:0044774 mitotic DNA integrity checkpoint signaling
Cellular Component
GO:0000793 condensed chromosome
GO:0005634 nucleus
GO:0035861 site of double-strand break

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3hot, PDBe:3hot, PDBj:3hot
PDBsum3hot
PubMed19766564
UniProtQ7JQ07|MOS1T_DROMA Mariner Mos1 transposase (Gene Name=mariner\T)

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