Structure of PDB 3hn8 Chain A Binding Site BS02

Receptor Information
>3hn8 Chain A (length=279) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPD
RKKKFQTKVHRKTLNPIFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHD
LIGQVVLDNLLELAEQPPDRPLWRDILEGGSEKADLGELNFSLCYLPTAG
LLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNP
TYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPEAADPHG
REHWAEMLANPRKPVEHWHQLVEEKTLSS
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain3hn8 Chain A Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3hn8 Molecular mechanism of the synaptotagmin-SNARE interaction in Ca2+-triggered vesicle fusion.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		D388 S391 R392 D394
Binding residue
(residue number reindexed from 1)		D94 S97 R98 D100
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:3hn8, PDBe:3hn8, PDBj:3hn8
PDBsum3hn8
PubMed20173762
UniProtP40748|SYT3_RAT Synaptotagmin-3 (Gene Name=Syt3)

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