Structure of PDB 3h8r Chain A Binding Site BS02

Receptor Information
>3h8r Chain A (length=204) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HSWRHIRAEGLDSSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFGK
WHSVPRKQATYGDAGLTYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFN
FVLINRYKDGSDHIGEHRDDCRELAPGSPIASVSFGASRDFVFRHKDSRG
KSPSRRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPVRKKVLAPRVNLTFR
KILL
Ligand information
Receptor-Ligand Complex Structure
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PDB3h8r Structure determination of DNA methylation lesions N1-meA and N3-meC in duplex DNA using a cross-linked protein-DNA system.
Resolution1.77 Å
Binding residue
(original residue number in PDB)		F102 G103 K104 H106 K205 R241 K242
Binding residue
(residue number reindexed from 1)		F48 G49 K50 H52 K151 R187 K188
Enzymatic activity
Enzyme Commision number 1.14.11.33: DNA oxidative demethylase.
Gene Ontology

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Biological Process
External links
PDB RCSB:3h8r, PDBe:3h8r, PDBj:3h8r
PDBsum3h8r
PubMed20223766
UniProtQ6NS38|ALKB2_HUMAN DNA oxidative demethylase ALKBH2 (Gene Name=ALKBH2)

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