Structure of PDB 3h1c Chain A Binding Site BS02

Receptor Information
>3h1c Chain A (length=544) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLNPIVRKFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTVVGQKKA
KPGQDFFPLTVNYQERTYAAGRIPGSFFRREGRPSEGETLIARLIDRPIR
PLFPEGFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIG
AARVGYINDQYVLNPTQDELKESKLDLVVAGTEAAVLMVESEAQLLSEDQ
MLGAVVFGHEQQQVVIQNINELVKEAGKPRWDWQPEPVNEALNARVAALA
EARLSDAYRITDKQERYAQVDVIKSETIATLLAEDETLDENELGEILHAI
EKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQA
LVTATLGTARDAQVLDELMGERTDTFLFHYNFPPYSVGETGMVGSPKRRE
IGHGRLAKRGVLAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLAL
MDAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDMDFKVAGSRD
GISALQMDIKIEGITKEIMQVALNQAKGARLHILGVMEQAINAP
Ligand information
>3h1c Chain F (length=21) Species: 83333 (Escherichia coli K-12) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GAAGGHTATHHASAAPARPQP
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3h1c Crystal structure of Escherichia coli polynucleotide phosphorylase core bound to RNase E, RNA and manganese: implications for catalytic mechanism and RNA degradosome assembly
Resolution3.57 Å
Binding residue
(original residue number in PDB)		V6 K8 E19 M22 M32 D36
Binding residue
(residue number reindexed from 1)		V6 K8 E19 M22 M32 D36
Enzymatic activity
Enzyme Commision number 2.7.7.8: polyribonucleotide nucleotidyltransferase.
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004654 polyribonucleotide nucleotidyltransferase activity
Biological Process
GO:0006396 RNA processing
GO:0006402 mRNA catabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3h1c, PDBe:3h1c, PDBj:3h1c
PDBsum3h1c
PubMed19327365
UniProtP05055|PNP_ECOLI Polyribonucleotide nucleotidyltransferase (Gene Name=pnp)

[Back to BioLiP]