Structure of PDB 3gqc Chain A Binding Site BS02

Receptor Information
>3gqc Chain A (length=435) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDCNFISNFYSHSRLHHISMWKCELTEFVNTLQRFPGREKLKKQSCIMHV
DMDCFFVSVGIRNRPDLKGKPVAVTSNRGTGRAPLRPGANPQLEWQYYQN
KILKGIDSVLSRAEIASCSYEARQLGIKNGMFFGHAKQLCPNLQAVPYDF
HAYKEVAQTLYETLASYTHNIEAVSCDEALVDITEILAETKLTPDEFANA
VRMEIKDQTKCAASVGIGSNILLARMATRKAKPDGQYHLKPEEVDDFIRG
QLVTNLPGVGHSMESKLASLGIKTCGDLQYMTMAKLQKEFGPKTGQMLYR
FCRGLDDRPVRTEKERKSVSAEINYGIRFTQPKEAEAFLLSLSEEIQRRL
EATGMKGKRLTLKIMVRKPGAPVETAKFGGHGICDNIARTVTLDQATDNA
KIIGKAMLNMFHTMKLNISDMRGVGIHVNQLVPTN
Ligand information
Receptor-Ligand Complex Structure
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PDB3gqc Structure of the human Rev1-DNA-dNTP ternary complex.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		F352 Y353 H355 S356 R357 L358 H359 S362 S448 A455 P456 S504 R505 A506 K686 T687 R709 K710 S713 A714 E715 N717 Y718 R742 K770 F771 G773 H774 G775
Binding residue
(residue number reindexed from 1)		F9 Y10 H12 S13 R14 L15 H16 S19 S76 A83 P84 S111 R112 A113 K293 T294 R316 K317 S320 A321 E322 N324 Y325 R349 K377 F378 G380 H381 G382
Enzymatic activity
Enzyme Commision number 2.7.7.-
Gene Ontology
Molecular Function
GO:0003684 damaged DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:3gqc, PDBe:3gqc, PDBj:3gqc
PDBsum3gqc
PubMed19464298
UniProtQ9UBZ9|REV1_HUMAN DNA repair protein REV1 (Gene Name=REV1)

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