Structure of PDB 3gi0 Chain A Binding Site BS02

Receptor Information
>3gi0 Chain A (length=203) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PQITLWKRPLVTIRIGGQLKEALLDTGADDTVIEELNLPGCWKPKLIGGI
AGFIKVRQYDQIPVEIAGHKAIGTVLVGPTPVNIIGRNLLTQIGATLNFC
GGGGPQITLWKRPLVTIRIGGQLKEALLDTGADDTVIEELNLPGCWKPKL
IGGIAGFIKVRQYDQIPVEIAGHKAIGTVLVGPTPVNIIGRNLLTQIGAT
LNF
Ligand information
Receptor-Ligand Complex Structure
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PDB3gi0 Correlations of protein dynamics with function in HIV-1 protease catalysis
Resolution1.8 Å
Binding residue
(original residue number in PDB)		D25 G27 A28 D29 G48 P81 V82 I84 R112 D129 G131 A132 D133 D134 I151 G152 G153 I154
Binding residue
(residue number reindexed from 1)		D25 G27 A28 D29 G48 P81 V82 I84 R112 D129 G131 A132 D133 D134 I151 G152 G153 I154
Enzymatic activity
Catalytic site (original residue number in PDB) D25 T26 G27
Catalytic site (residue number reindexed from 1) D25 T26 G27
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
3.4.23.16: HIV-1 retropepsin.
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:3gi0, PDBe:3gi0, PDBj:3gi0
PDBsum3gi0
PubMed
UniProtP03369|POL_HV1A2 Gag-Pol polyprotein (Gene Name=gag-pol)

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