Structure of PDB 3gcm Chain A Binding Site BS02

Receptor Information
>3gcm Chain A (length=544) Species: 331111 (Escherichia coli O139:H28 str. E24377A) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LNPIVRKFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTVVGQKKAK
PGQDFFPLTVNYQERTYAAGRIPGSFFRREGRPSEGETLIARLIDRPIRP
LFPEGFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIGA
ARVGYINDQYVLNPTQDELKESKLDLVVAGTEAAVLMVESEAELLSEDQM
LGAVVFGHEQQQVVIQNINELVKEAGKPRWDWQPEPVNEALNARVAALAE
ARLSDAYRITDKQERYAQVDVIKSETIATLLAEDETLDENELGEILHAIE
KNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQAL
VTATLGTARDAQVLDELMGERTDTFLFHYNFPPYSVGETGMVGSPKRREI
GHGRLAKRGVLAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLALM
DAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDMDFKVAGSRDG
ISALQMDIKIEGITKEIMQVALNQAKGARLHILGVMEQAINAPR
Ligand information
>3gcm Chain F (length=21) Species: 562 (Escherichia coli) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GAAGGHTATHHASAAPARPQP
Receptor-Ligand Complex Structure
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PDB3gcm Crystal structure of Escherichia coli polynucleotide phosphorylase core bound to RNase E, RNA and manganese: implications for catalytic mechanism and RNA degradosome assembly.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		V6 T17 E19 M22 M32 S34 D37
Binding residue
(residue number reindexed from 1)		V5 T16 E18 M21 M31 S33 D36
Enzymatic activity
Enzyme Commision number 2.7.7.8: polyribonucleotide nucleotidyltransferase.
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004654 polyribonucleotide nucleotidyltransferase activity
Biological Process
GO:0006396 RNA processing
GO:0006402 mRNA catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3gcm, PDBe:3gcm, PDBj:3gcm
PDBsum3gcm
PubMed19327365
UniProtA7ZS61|PNP_ECO24 Polyribonucleotide nucleotidyltransferase (Gene Name=pnp)

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