Structure of PDB 3g8x Chain A Binding Site BS02

Receptor Information
>3g8x Chain A (length=76) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKI
RRKNCPACRYRKCLQAGMNLEARKTK
Ligand information
Receptor-Ligand Complex Structure
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PDB3g8x DNA binding site sequence directs glucocorticoid receptor structure and activity.
Resolution2.05 Å
Binding residue
(original residue number in PDB)
C450 H451 Y452 K461 K465 R510
Binding residue
(residue number reindexed from 1)
C13 H14 Y15 K24 K28 R73
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:3g8x, PDBe:3g8x, PDBj:3g8x
PDBsum3g8x
PubMed19372434
UniProtP06536|GCR_RAT Glucocorticoid receptor (Gene Name=Nr3c1)

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