Structure of PDB 3fvq Chain A Binding Site BS02

Receptor Information

>3fvq Chain A (length=343) Species: 242231 (Neisseria gonorrhoeae FA 1090)

TAALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLA
GFEQPDSGEISLSGKTIFSKNTNLPVRERRLGYLVQEGVLFPHLTVYRNI
AYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRAALAR
ALAPDPELILLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREE
ALQYADRIAVMKQGRILQTASPHELYRQPADLDAALFIGEGIVFPAALNA
DGTADCRLGRLPVQSGAPAGTRGTLLIRPEQYSLHPHSAPAASIHAVVLK
TTPKARHTEISLRAGQTVLTLNLLSDGISAVLHLDGPALFFPG

Ligand information

• Ligand ID: CA
• InChI: InChI=1S/Ca/q+2
• InChIKey: BHPQYMZQTOCNFJ-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Ca++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Ca+2]
• Formula: Ca
• Name: CALCIUM ION
• DrugBank: DB14577
• PDB chain: 3fvq Chain A Residue 360

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3fvq Insights into how nucleotide-binding domains power ABC transport.
• Resolution: 1.9 Å
• Binding residue (original residue number in PDB): T44 Q87
• Binding residue (residue number reindexed from 1): T43 Q86
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 7.2.2.7: ABC-type Fe(3+) transporter.

Gene Ontology

Molecular Function

• GO:0005524 ATP binding
• GO:0015408 ABC-type ferric iron transporter activity
• GO:0016887 ATP hydrolysis activity

Biological Process

• GO:0006826 iron ion transport
• GO:0034755 iron ion transmembrane transport
• GO:0098655 monoatomic cation transmembrane transport

Cellular Component

• GO:0005886 plasma membrane
• GO:0016020 membrane

External links

• PDB: RCSB:3fvq, PDBe:3fvq, PDBj:3fvq
• PDBsum: 3fvq
• PubMed: 19748342
• UniProt: Q5FA19|FBPC_NEIG1 Fe(3+) ions import ATP-binding protein FbpC (Gene Name=fbpC)