Structure of PDB 3fvb Chain A Binding Site BS02

Receptor Information

>3fvb Chain A (length=161) Species: 359391 (Brucella abortus 2308) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GSMKGEPKVIERLNEALFLELGAVNQYWLHYRLLNDWGYTRLAKKEREES
IEEMHHADKLIDRIIFLEGFPNLQTVSPLRIGQNVKEVLEADLKGEYDAR
ASYKESREICDKLGDYVSKQLFDELLADEEGHIDFLETQLDLLAKIGGER
YGQLNAAPADE

Ligand information

Ligand ID

InChI

InChI=1S/Fe/q+3

InChIKey

VTLYFUHAOXGGBS-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 CACTVS 3.341 OpenEye OEToolkits 1.5.0	[Fe+3]

Formula

Name

FE (III) ION

PDB chain

3fvb Chain A Residue 164 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	3fvb Crystal structure of ferritin from Brucella melitensis
Resolution	1.806 Å
Binding residue (original residue number in PDB)	E18 E51 H54 E127
Binding residue (residue number reindexed from 1)	E20 E53 H56 E129
Annotation score	5

Enzymatic activity

Enzyme Commision number

1.16.3.1: ferroxidase.

Gene Ontology

	Molecular Function
GO:0004322	ferroxidase activity
GO:0005506	iron ion binding
GO:0008199	ferric iron binding
GO:0020037	heme binding
GO:0046872	metal ion binding

	Biological Process
GO:0006826	iron ion transport
GO:0006879	intracellular iron ion homeostasis
GO:0006880	intracellular sequestering of iron ion

	Cellular Component
GO:0005829	cytosol

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Molecular Function

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Cellular Component

External links

PDB	RCSB:3fvb, PDBe:3fvb, PDBj:3fvb
PDBsum	3fvb
PubMed
UniProt	Q2YKI4

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