Structure of PDB 3fiv Chain A Binding Site BS02

Receptor Information
>3fiv Chain A (length=111) Species: 11673 (Feline immunodeficiency virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TTTTLEKRPEILIFVNGYPIKFLLNTGADITILNRRDFQVKNSIENGRQN
MIGVGGGKRGTNYINVHLEIRDENYKTQCIFGNVCVLEDNSLIQPLLGRD
NMIKFNIRLVM
Ligand information
Receptor-Ligand Complex Structure
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PDB3fiv Crystal structures of the inactive D30N mutant of feline immunodeficiency virus protease complexed with a substrate and an inhibitor.
Resolution1.85 Å
Binding residue
(original residue number in PDB)		R13 N30 G32 A33 D34 I35 M56 I57 V59 I98 Q99 L101
Binding residue
(residue number reindexed from 1)		R8 N25 G27 A28 D29 I30 M51 I52 V54 I93 Q94 L96
Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
3.4.23.-
3.6.1.23: dUTP diphosphatase.
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:3fiv, PDBe:3fiv, PDBj:3fiv
PDBsum3fiv
PubMed9271500
UniProtP16088|POL_FIVPE Pol polyprotein (Gene Name=pol)

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