Structure of PDB 3fea Chain A Binding Site BS02

Receptor Information
>3fea Chain A (length=83) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVY
CGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVT
Ligand information
Receptor-Ligand Complex Structure
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PDB3fea Crystal Structures of Human MdmX (HdmX) in Complex with p53 Peptide Analogues Reveal Surprising Conformational Changes
Resolution1.33 Å
Binding residue
(original residue number in PDB)
Q26 V49 K50 T108
Binding residue
(residue number reindexed from 1)
Q1 V24 K25 T83
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0043066 negative regulation of apoptotic process
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus

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Biological Process

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Cellular Component
External links
PDB RCSB:3fea, PDBe:3fea, PDBj:3fea
PDBsum3fea
PubMed19153082
UniProtO15151|MDM4_HUMAN Protein Mdm4 (Gene Name=MDM4)

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