Structure of PDB 3fea Chain A Binding Site BS02
Receptor Information
>3fea Chain A (length=83) Species:
9606
(Homo sapiens) [
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QVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVY
CGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVT
Ligand information
>3fea Chain M (length=8) [
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FMAFWEPL
Receptor-Ligand Complex Structure
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PDB
3fea
Crystal Structures of Human MdmX (HdmX) in Complex with p53 Peptide Analogues Reveal Surprising Conformational Changes
Resolution
1.33 Å
Binding residue
(original residue number in PDB)
Q26 V49 K50 T108
Binding residue
(residue number reindexed from 1)
Q1 V24 K25 T83
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Biological Process
GO:0043066
negative regulation of apoptotic process
GO:0051726
regulation of cell cycle
Cellular Component
GO:0005634
nucleus
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Biological Process
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Cellular Component
External links
PDB
RCSB:3fea
,
PDBe:3fea
,
PDBj:3fea
PDBsum
3fea
PubMed
19153082
UniProt
O15151
|MDM4_HUMAN Protein Mdm4 (Gene Name=MDM4)
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