Structure of PDB 3fde Chain A Binding Site BS02

Receptor Information
>3fde Chain A (length=209) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MPANHFGPIPGVPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVL
AGGYEDDVDNGNYFTYTGSGGRDLSGNKRTAGQSSDQKLTNNNRALALNC
HSPINEKGAEAEDWRQGKPVRVVRNMKGGKHSKYAPAEGNRYDGIYKVVK
YWPERGKSGFLVWRYLLRRDDTEPEPWTREGKDRTRQLGLTMQYPEGYLE
ALANKEKSR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3fde UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications.
Resolution1.41 Å
Binding residue
(original residue number in PDB)		R448 H450 H455 R457 S458 N494 R496 N508
Binding residue
(residue number reindexed from 1)		R31 H33 H38 R40 S41 N77 R79 N91
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
External links
PDB RCSB:3fde, PDBe:3fde, PDBj:3fde
PDBsum3fde
PubMed19077538
UniProtQ8VDF2|UHRF1_MOUSE E3 ubiquitin-protein ligase UHRF1 (Gene Name=Uhrf1)

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