Structure of PDB 3f9y Chain A Binding Site BS02

Receptor Information
>3f9y Chain A (length=159) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SKAELQSEERKRIDELIESGKEEGMKIDLIDGKGRGVIATKQFSRGDFVV
EYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYLSKTYCVDATRETNRL
GRLINHSKCGNCQTKLHDIDGVPHLILIASRDIAAGEELLFDYGDRSKAS
IEAHPWLKH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3f9y Structural origins for the product specificity of SET domain protein methyltransferases.
Resolution1.5 Å
Binding residue
(original residue number in PDB)		L222 R228
Binding residue
(residue number reindexed from 1)		L29 R35
Enzymatic activity
Enzyme Commision number 2.1.1.-
2.1.1.361: [histone H4]-lysine(20) N-methyltransferase.
Gene Ontology
Molecular Function
GO:0042799 histone H4K20 methyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:3f9y, PDBe:3f9y, PDBj:3f9y
PDBsum3f9y
PubMed19088188
UniProtQ9NQR1|KMT5A_HUMAN N-lysine methyltransferase KMT5A (Gene Name=KMT5A)

[Back to BioLiP]