Structure of PDB 3f3q Chain A Binding Site BS02

Receptor Information
>3f3q Chain A (length=109) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HHHHHHMVTQFKTASEFDSAIAQDKLVVVDFYATWCGPCKMIAPMIEKFS
EQYPQADFYKLDVDELGDVAQKNEVSAMPTLLLFKNGKEVAKVVGANPAA
IKQAIAANA
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3f3q Chain A Residue 105 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3f3q Structural and kinetic analysis of Saccharomyces cerevisiae thioredoxin Trx1: implications for the catalytic mechanism of GSSG reduced by the thioredoxin system
Resolution1.76 Å
Binding residue
(original residue number in PDB)		H-2 H0
Binding residue
(residue number reindexed from 1)		H4 H6
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0015035 protein-disulfide reductase activity
GO:0015036 disulfide oxidoreductase activity
Biological Process
GO:0000011 vacuole inheritance
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
GO:0009263 deoxyribonucleotide biosynthetic process
GO:0015031 protein transport
GO:0042144 vacuole fusion, non-autophagic
GO:0045454 cell redox homeostasis
Cellular Component
GO:0000139 Golgi membrane
GO:0000324 fungal-type vacuole
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005758 mitochondrial intermembrane space
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0016020 membrane
GO:0120124 membrane fusion priming complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3f3q, PDBe:3f3q, PDBj:3f3q
PDBsum3f3q
PubMed19362171
UniProtP22217|TRX1_YEAST Thioredoxin-1 (Gene Name=TRX1)

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